galidesivir bcx4430 Search Results


galidesivir bcx4430  (MedChemExpress)
94
MedChemExpress galidesivir bcx4430
Galidesivir Bcx4430, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/galidesivir+bcx4430/Galidesivir/pm41936880-72-9-16
Average 94 stars, based on 1 article reviews
galidesivir bcx4430 - by Bioz Stars, 2026-10
94/100 stars
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galidesivir  (MedChemExpress)
93
MedChemExpress galidesivir
NHC inhibits BRBV infection in cell culture. ( A through D ) A549 cells inoculated with BRBV (MOI of 0.01) in the presence or absence of different concentrations of ( A ) NHC, ( B ) <t>galidesivir,</t> ( C ) remdesivir, and ( D ) sofosbuvir. The virus titer in the culture supernatant was quantified in 12, 24, 48, and 72 h. Values are means (± standard error of the mean) of the virus titer from three experiments performed in duplicate. ** P < 0.01, *** P < 0.005 by one-way ANOVA on the area under the curves fit by linear regression of log-transformed virus titer over time and compared with Dunnett’s multiple comparisons. The dotted line represents the limit of detection at 200 FFU/mL. ( E ) Inhibition comparison of NHC and favipiravir in A549 cells at 48 hpi, including the indicated 50% effective concentration (EC 50 ). A curve was fitted through the data using the log(inhibitor) vs. response-variable slope equation (GraphPad Prism 10.0).
Galidesivir, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/galidesivir+bcx4430/Galidesivir+hydrochloride/pmc12548437-48-25-26
Average 93 stars, based on 1 article reviews
galidesivir - by Bioz Stars, 2026-10
93/100 stars
  Buy from Supplier

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NHC inhibits BRBV infection in cell culture. ( A through D ) A549 cells inoculated with BRBV (MOI of 0.01) in the presence or absence of different concentrations of ( A ) NHC, ( B ) galidesivir, ( C ) remdesivir, and ( D ) sofosbuvir. The virus titer in the culture supernatant was quantified in 12, 24, 48, and 72 h. Values are means (± standard error of the mean) of the virus titer from three experiments performed in duplicate. ** P < 0.01, *** P < 0.005 by one-way ANOVA on the area under the curves fit by linear regression of log-transformed virus titer over time and compared with Dunnett’s multiple comparisons. The dotted line represents the limit of detection at 200 FFU/mL. ( E ) Inhibition comparison of NHC and favipiravir in A549 cells at 48 hpi, including the indicated 50% effective concentration (EC 50 ). A curve was fitted through the data using the log(inhibitor) vs. response-variable slope equation (GraphPad Prism 10.0).

Journal: Journal of Virology

Article Title: Molnupiravir inhibits Bourbon virus infection and disease-associated pathology in mice

doi: 10.1128/jvi.00740-25

Figure Lengend Snippet: NHC inhibits BRBV infection in cell culture. ( A through D ) A549 cells inoculated with BRBV (MOI of 0.01) in the presence or absence of different concentrations of ( A ) NHC, ( B ) galidesivir, ( C ) remdesivir, and ( D ) sofosbuvir. The virus titer in the culture supernatant was quantified in 12, 24, 48, and 72 h. Values are means (± standard error of the mean) of the virus titer from three experiments performed in duplicate. ** P < 0.01, *** P < 0.005 by one-way ANOVA on the area under the curves fit by linear regression of log-transformed virus titer over time and compared with Dunnett’s multiple comparisons. The dotted line represents the limit of detection at 200 FFU/mL. ( E ) Inhibition comparison of NHC and favipiravir in A549 cells at 48 hpi, including the indicated 50% effective concentration (EC 50 ). A curve was fitted through the data using the log(inhibitor) vs. response-variable slope equation (GraphPad Prism 10.0).

Article Snippet: Next, the cells were treated with different concentrations of remdesivir (Selleckchem; S8932), sofosbuvir (Selleckchem; S2794), N 4 -hydroxycytidine (NHC; Selleckchem; S0833), favipiravir (Selleckchem; S7975), or galidesivir (MedChemExpress; HY-18649/CS-3778) for 2 h in serum-free DMEM.

Techniques: Infection, Cell Culture, Virus, Transformation Assay, Inhibition, Comparison, Concentration Assay